The winner is... you. If you eat moderately. Chicken wins for sodium control and versatility. Shrimp wins for omega-3s and low saturated fat. They’re like two different bands at a music festival—both can rock your world, but you wouldn’t put them in the same mosh pit.
If you want a direct cholesterol comparison? Chicken breast is lower in cholesterol, but shrimp is friendlier to your blood lipid profile. That’s science-speak for “it’s complicated.” One older study even showed that shrimp slightly raised HDL (the good cholesterol) in some people—like a tiny superhero cape for your blood.
In the end, choose the one that makes your taste buds do the cha-cha. But if you’re really stressed, eat both. Make a stir-fry. Call it “surf and turf for the indecisive.” Your heart can handle it, as long as you don’t deep-fry everything in bacon grease. Now go cook something, you magnificent cholesterol warrior.