Full pan, fully assembled, cold from fridge: 375°F, covered for 35 mins, uncovered for 15-20 mins. Total: about 50-60 minutes. Let it rest for 10 minutes before cutting—this keeps the layers from sliding into a saucy disaster.
Half pan or single serving? Cut the time by about 15 minutes. Use the same foil trick. A small ramekin full of lasagna is like a personal pizza—faster, and all yours.